Publications by authors named "V N Nichols"

Article Synopsis
  • The Chronic Headache Education and Self-management Study (CHESS) aimed to develop supportive strategies for individuals suffering from chronic headaches, revealing a lack of qualitative research on their lived experiences.
  • Researchers conducted semi-structured interviews with participants from the CHESS study, analyzing the results through thematic analysis to understand the complexities of living with chronic headaches.
  • The study identified six major themes related to the emotional impact and nature of headaches, alongside four overlapping categories of headache impact, highlighting the varying degrees to which headaches affect participants' lives over time.
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Objective: To evaluate whether a structured online supervised group physical and mental health rehabilitation programme can improve health related quality of life compared with usual care in adults with post-covid-19 condition (long covid).

Design: Pragmatic, multicentre, parallel group, superiority randomised controlled trial.

Setting: England and Wales, with home based interventions delivered remotely online from a single trial hub.

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Background: The Improving the Wellbeing of people with Opioid Treated CHronic pain (I-WOTCH) randomised controlled trial found that a group-based educational intervention to support people using strong opioids for chronic non-malignant pain helped a significant proportion of people to stop or decrease opioid use with no increase in pain-related disability. We report a linked process evaluation of the group-based intervention evaluated in comparison to a usual-care control group that received a self-help booklet and relaxation CD.

Methods: We interviewed 18 intervention facilitators, and 20 intervention and 20 control participants who had chronic non-malignant pain and were recruited from general (family) practices in the UK.

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Importance: Opioid use for chronic nonmalignant pain can be harmful.

Objective: To test whether a multicomponent, group-based, self-management intervention reduced opioid use and improved pain-related disability compared with usual care.

Design, Setting, And Participants: Multicentered, randomized clinical trial of 608 adults taking strong opioids (buprenorphine, dipipanone, morphine, diamorphine, fentanyl, hydromorphone, methadone, oxycodone, papaveretum, pentazocine, pethidine, tapentadol, and tramadol) to treat chronic nonmalignant pain.

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