Time course of changes was studied in parameters characterizing lipid peroxidation (LPO) and the total lipids counts in red cell membranes (RCM) and blood plasma (BP) of patients with hypertensive disease (HD) and arterial hypertension in chronic pyelonephritis against the background of diabetes mellitus (DM). The study groups were DM patients (group I), those with coexistent HDDM (group II), and those with arterial hypertension caused by chronic pyelonephritis in the presence of DM (group III). All three groups of patients demonstrated intensification of the cellular membrane- and blood plasma LPO as well as increase in the total lipids counts.
View Article and Find Full Text PDFTime course was studied of indices for lipid peroxidation (LPO) and total lipids count in erythrocytic membranes (EM) and blood plasma (BP) of patients with essential hypertension (EH) associated with diabetes mellitus (DM), under the effect of alpha-tocopherol. EH patients demonstrated intensification of LPO in cellular membranes and BP. Association of EH with DM is responsible for a more significant increase of the levels of accumulation of LPO products in EM and rise in total lipids content both in cellular membranes and BP.
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