P2 purinergic receptor expression is dysregulated in multiple cancer subtypes and is associated with worse outcomes. Studies identify roles for P2 purinergic receptors in tumor cells that drive disease aggressiveness. There is also sufficient evidence that P2 purinergic receptor expression within the tumor microenvironment (TME) is critical for disease initiation and progression.
View Article and Find Full Text PDFDental radiography is widely used in dental practices and offers a valuable resource for the development of AI technology. Consequently, many researchers have been drawn to explore its application in different areas. The current systematic review was undertaken to critically appraise developments and performance of artificial intelligence (AI) models designed for tooth numbering and detection using dento-maxillofacial radiographic images.
View Article and Find Full Text PDFSoft materials made from braided or woven microscale fibers can display unique properties that can be exploited in electromagnetic, mechanical, and biomedical applications. These properties depend on the topology of the braids or weaves-that is, the order in which fibers cross one another. Current industrial braiding and weaving machines cannot easily braid or weave micrometer-scale fibers into controllable topologies; they typically apply forces that are large enough to break the fibers, and each machine can typically make only one topology.
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