[Modeling of the "universal" bone marrow using monoclonal antibodies].

The data on the application of monoclonal antibodies (ICO-10) and rabbit complement for working the conditions of allogeneic bone marrow transplantation are presented in the paper. The treatment with monoclonal antibodies and bone marrow complement from BALB/c mice for 2 times prevented the development of transplant versus host reaction and completely protected lethally irradiated (CBA X X C57B1/6)FI mice-recipients from death. Thymus atrophy and the absence of T-cells in the peripheral blood was observed in these mice.

[ICO-10 monoclonal antibodies to the Thy-1 antigen].

Mouse monoclonal antibodies (MAB) ICO-10 to Thy-1 antigen were obtained. MAB ICO-10 reacted in indirect immunofluorescence test with 5.7 +/- 0.

[Inhibition of the growth of the Ca-755 tumor in mice with reconstitution of hematopoiesis].

Data on the growth inhibition of Ca-755 tumor transplanted to mice two months after hemopoiesis recovery with syngeneic bone marrow cells or allogeneic fetal liver are presented.