Xylate effect on the renal toxicological function with diabetes mellitus complicated by endogenous intoxication syndrome of purulent-septic genesis.

Objective: Aim: To study xylate effect on the renal toxin-excreting function with diabetes mellitus (DM) complicated by endogenous intoxication syndrome of purulentseptic genesis.

Patients And Methods: Materials and Methods: The effect of infusions with sorbilact or Ringer's solution in the regimen 3 ml/kg/hour during 3 hours on toxin-excreting function of the kidneys in patients with type 2 DM complicated by EIS is studied.

Results: Results: In the period of the research, xylate increased cleaning blood plasma (extracellular water space) from the total toxicity by 6,0±1,9 ml/min (230±72,3%, Δ р<0,05).

THE STATE OF TOXIN-RELEASING FUNCTION OF THE KIDNEYS IN THE SYNDROME OF ENDOGENOUS INTOXICATION OF PURULENT-SEPTIC ORIGIN IN PATIENTS WITH DIABETES MELLITUS.

Objective: The aim: To investigate the state of renal toxin excretory function in EIS of purulent-septic genesis in patients with diabetes mellitus-2 under the condition of infusion load with low-volume Ringer's solution.

Patients And Methods: Materials and methods: The research belongs to the opened, randomized, prospective and controlled studies. The study group was consisted of patients with diabetes mellitus-2 complicated syndrome of endogenous intoxication of purulent-septic origin (CDSEI).

The condition of volumetric and osmoregulatory function of the kidneys in toxicemia of purulent-septic genesis in patients with diabetes mellitus.

Objective: The aim of the study is to investigate the state of volumetric and osmoregulatory function of the kidneys in diabetes complicated by the syndrome of the endogenous intoxication of purulent-septic genesis.

Patients And Methods: Materials and methods: The study group was consisted of patients with insulin-dependent diabetes mellitus with complicated syndrome of the endogenous intoxication of purulent-septic genesis (CSDI).

Results: Results: The starting indices of volumetric and osmoregulatory function of the kidneys in patients with INCs complicated by the endogenous intoxication of purulent-septic genesis (CEI GHG) syndrome are characterized by the values of the inhibition of the volumorregulatory (by the clearance of sodium by 11%, p <0.

[The regulation of water-salt exchange in a disorder of the integrity of the lymph circulation system].

The mechanisms regulating the water-salt metabolism have been investigated in the experiment on dogs with a disturbance of the lymph flow system. The function of a regulator of the water-salt metabolism is found to be peculiar to the lymphatic system which is effected by means of the humoral properties of the lymph and discreteness of its static pressure in the thoracic lymphatic duct. The central lymph exerts a stabilizing effect on both the osmo- and volumoregulatory functions of the kidneys, cardio- and hemodynamics.