[Effectiveness of cyclosporin A in the treatment of adult patients with aplastic anemia].

Aim: To evaluate the efficacy of cyclosporin A (CyA) at different stages of immunosuppressive therapy (IST) in patients with aplastic anemia (AA).

Materials And Methods: The efficacy of CyA was studied in 56 patients with AA. The agent was orally given in an initial dose of 10 mg/kg as solution or capsules.

[Aplastic anemia and viral hepatitis (posthepatitic aplastic anemia)].

Aim: To validate up-to-date policy of immunosuppressive therapy of patients with aplastic anemia (AA) which has developed either at acute or chronic phase of viral hepatitis.

Materials And Methods: 16 patients with AA detected within 6 months (9 patients) or 12-36 months (7 patients) after acute viral hepatitis received immunosuppressive therapy (antilymphocytic globulin, cyclosporin A, splenectomy).

Results: Posthepatitis aplastic anemias ran a severe and treatment-resistant course in most cases.