Reactive Changes in Lymph Node Structure in Peritonitis and during Treatment with a New Antibiotic.

The effect of a new antibiotic peptomide A-70 on changes in the mesenterial lymph nodes caused by experimental peritonitis was studied. Differences in the morphological changes in rat lymph nodes in peritonitis and against the background of antibiotic therapy were revealed. Lymph nodes responded to peritoneal inflammation by reducing the area of cortical structures and expansion of the sinus system, which indicates a decrease in drainage-detoxification and immune function and determines unfavorable outcome of peritonitis.

[PERIPHERAL LYMPHOID STRUCTURES: FORMATION AND FUNCTION].

The problem of the formation of new lymphoid structures (neolymphogenesis) is quite controversial and widely discussed in the literature. Under normal conditions, lymphoid organs arise only in the process of fetal development (organogenesis), however in long-standing chronic inflammatory processes, nonhealing wounds, autoimmune diseases, oncologic pathology spontaneous formation of new lymphoid structures was noted. The structures of the peripheral lymphoid formations include the lymphocytes arranged singly and in clusters (infiltration), lymphoid nodules and lymph nodes.

Lymph Region in the Female Internal Reproductive Organs during the Early Postpartum Period after Normal Pregnancy.

The structural and functional changes in the lymph region of the female internal reproductive organs in rats were studied during the early postpartum period after normal pregnancy. The results indicated that the main role of the lymph region in pregnancy consisted in supporting sufficient lymph production and drainage in the hypertrophic uterus.

[Increase of drainage and immune functions of the lymph node as a factor of endoecological well-being in elderly and senile age].

Age-related changes in mesocolic lymph node reflect the general process of ageing. In lymph node, these changes are associated with size reduction of structural and functional areas in the setting of manganese excess and iron, zinc, and selenium deficiency, which determines the reduction of lymphoid tissue functional activity in elderly and senile ages. We have realized the idea to control the lymphatic system functions using phytotherapy.