Publications by authors named "V N Goral"
Article Synopsis
- This study focuses on creating a new fixed bed bioreactor designed for scalable adherent cell culture, which is vital for advancing cell and gene therapies.
- The bioreactor features stacked mesh discs for efficient fluid flow and minimal stress on cells, showing excellent uniformity in media distribution during cell growth.
- The platform is highly effective for automated cell harvesting and maintains a high cell viability rate while allowing for predictable modeling of cell growth, making it a promising tool for large-scale biomanufacturing.
Article Synopsis
- - The study aimed to explore the incidence of celiac disease (CD) in patients diagnosed with microscopic colitis (MC) and to differentiate the characteristics of both conditions.
- - The research involved 90 MC patients and found that only 1.1% had CD, with minimal positivity for various autoantibodies, indicating a low correlation between the two diseases.
- - Notably, an increase in intraepithelial lymphocytes (IEL) was identified in MC patients who did not respond to treatment, but overall, the study did not support the idea that CD is more prevalent among MC patients.
Gastric varices are less common than esophageal varices, and their treatment is quite challenging. Gastric varix bleedings (GVB) occur less frequently than esophageal varix (EV) bleedings and represent 10% to 30% of all variceal bleedings. They are; however, more severe and are associated with high mortality.
View Article and Find Full Text PDFCholangiocarcinoma is a malignant neoplasm originating from biliary epithelial cells. The incidence and mortality of this cancer are rising in the world. Currently, cholangiocarcinoma is accepted as a stem cell disease with many risk factors.
View Article and Find Full Text PDFGastric cancer is a multifactorial and complex malignant disease seen commonly worldwide. It is one of the few malignant conditions in which the etiology involves infectious agents (Helicobacter pylori), but there are many other risk factors incuding high salt intake. Its pathogenesis generally involves interactions between environmental factors and genetic disposition.
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