Publications by authors named "V N Galkin"
[Impact of various rehabilitation programs on anxiety and depression after surgery of early-stage cervical cancer].
Vopr Kurortol Fizioter Lech Fiz Kult
November 2024
Article Synopsis
- Cervical cancer (CC) is increasingly common and presents significant health care challenges, even with HPV vaccination and screening efforts; there's a need to understand rehabilitation's role in reducing anxiety and depression post-surgery.
- A study involving 103 female CC patients compared two rehabilitation programs: one multicomponent and the other adhering to standard guidelines, assessing anxiety and depression levels pre-surgery and over 36 months post-op using the Hospital Anxiety and Depression Scale (HADS).
- Results showed that the multicomponent rehabilitation significantly decreased anxiety and depression more effectively than the standard program, highlighting its importance in recovery for early-stage CC patients.
Objective: To present treatment of primary esophageal melanoma in a young patient, as well as review of modern data on this issue.
Material And Methods: We describe the results of treatment of a patient with primary melanoma of the esophagus. PubMed, SCOPUS, and elibrary databases were used for the review.
Cardiac muscle contraction occurs due to repetitive interactions between myosin thick and actin thin filaments (TF) regulated by Ca levels, active cross-bridges, and cardiac myosin-binding protein C (cMyBP-C). The cardiac TF (cTF) has two nonequivalent strands, each comprised of actin, tropomyosin (Tm), and troponin (Tn). Tn shifts Tm away from myosin-binding sites on actin at elevated Ca levels to allow formation of force-producing actomyosin cross-bridges.
View Article and Find Full Text PDFMalignant neoplasms, including pancreatic cancer and melanoma, are major global health challenges. This study investigates melanoma pancreatic syndrome, a rare hereditary tumor syndrome associated with gene mutations. mutations contribute to a lifetime risk of melanoma ranging from 28% to 67%.
View Article and Find Full Text PDFObjective: Describe the structure of pathogenic germline variants and clinical and anatomical features in colorectal cancer patients in Moscow.
Material And Methods: The whole genome sequencing results of patients with suspected hereditary cancer syndrome were evaluated. All identified genetic variants were validated using Sanger sequencing.