[Ultrastructural characteristics of nonphlogogenic and phlogogenic reaction of mono- and polynuclear phagocytes in their interaction with Staphylococcus aureus].

Antibacterial function of neutrophil leukocytes and peritoneal macrophages in their interaction with massive doses of Staphylococcus aureus (25 x 10(6) and 25 x 10(8) microorganisms) has been studied in the experiment in vivo. Two types of antibacterial reaction of phagocytes has been found, i.e.

[Non-inflammatory form of neutrophil antibacterial response].

According to the Mechnikov theory inflammation is the only form of the protective-adaptive response of phagocytes and phagocytosis is its essence. High doses of Staphylococcus aureus (25 x 10(6) and 25 x 10(2) bacteria) in the absence of additional peritoneal damage do not produce the inflammation. The organism of the highest animals possess non-phlogogenic mechanisms of protection against bacteria when the phagocyte function is not the destruction of bacteria but their catching and transportation to the intestinal lumen.

[Ultrastructural characteristics in neutrophilic leukocytes in patients with sepsis].

Electron microscopic studies of neutrophilic leukocytes from patients with sepsis have revealed that substantial counts of these cells are prone to degradation just in the blood, the organelles of the degraded cells many of which may be identified are present in the blood plasma. The degradation of neutrophilic leukocytes in systemic circulation may be one of the morphological signs of sepsis.