[Separate and combined mutagenic effect of radiation and asbestos on the micronucleus test in experiments].

We investigated the isolated and combined mutagenic effect (ME) of radiation (gamma-irradiation, 0.5 or 2 Gy) and asbestos (i.p.

[Modified effect of dust and chemical mutagens under the influence of vibration].

The impact of transport vibration on the mutagenic effect (ME) of asbestos, benzo(a)pyrene (BaP), benzene, ortho-aminotoluene, and quinoline was studied. There was a decrease in ME of all the substances when they influenced erythrocytes simultaneously with 24-hour vibration. Decreased ME of BaP was seen during 2-month vibration, and ME increased during 3-day vibration.

[Effects of coal tar on hematological parameters in experimental tuberculosis].

Guinea pigs were injected with coal tar (CT) (intratracheally, 25 mg per animal once a week or a month for 2 or 8 months, respectively), then they were infected with MBT (H37Rv, 0.1 mg, subcutaneously). There were changes in hematological responses to MBT changes (in the context of the cell composition of bone marrow and peripheral blood), their pattern was associated with the mode of exposure to CT preceding MBT inoculation.

[Mutagenic effects of asbestos modified by association with ethanol, coffee and tobacco tar].

The study covered possible modification of mutagenic action of asbestos in combination with widespread agents--ethanol, coffee extractive and fumigating resin. Such modifying effects as antagonism, synergism were revealed as well as an independent action. An attempt was made to extrapolate the obtained data to human exposure to asbestos.