Publications by authors named "V N Felix"

Designing molecular receptors that bind anions in water is a significant challenge, and an even greater difficulty lies in using these receptors to remove anions from water without resorting to the hazardous liquid-liquid extraction approach. We here demonstrate an effective and synthetically simple strategy toward these goals by exploiting ion-pair assembly of macrocycles. Our anion binding ensemble consists of an octa-chloro tetra-urea macrocyclic anion receptor (ClTU), which forms water-dispersible aggregates, and a tetra-cationic fluorescent dye 5,10,15,20-tetrakis(1-methyl-4-pyridinio)porphyrin (TMPyP4), which provides Coulombic stabilization and fluorescence reporting of anion binding in an ion-pair assembly.

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  • Intense wildfires are increasingly impacting air quality, raising concerns about potential negative effects on cardiopulmonary health for people exposed to smoke, particularly in the Eastern US.
  • A study aimed to examine the relationship between smoke from wildfires in Western Canada and respiratory diseases in various demographic groups in Eastern US populations, using data from the University of Maryland Medical System.
  • Findings showed significantly higher rates of cardiopulmonary clinical encounters during "hotspot days" with elevated PM2.5 levels, indicating a correlation between increased pollution and health issues, especially during notable air quality deteriorations in June 2023.
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In rheumatoid arthritis (RA), the risk of cardiovascular death is 50% higher compared to the general population. This increased risk is partly due to the systemic inflammation characteristic of RA and changes in the lipoprotein profiles. This study investigated plasma lipid levels, lipid ratios, and the composition and functionality of high-density lipoprotein (HDL) in control individuals and RA subjects based on the disease's inflammatory score (DAS28).

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  • Internal carotid artery (ICA) injury is a significant concern during endoscopic sinus and skull base surgeries, often triggered by reliance on the vidian canal as a landmark.
  • A study using CT scans of 105 patients aimed to better locate the ICA by investigating the anatomical relationship between the palatovaginal canal (PVC) and the ICA's laceral genu.
  • Results showed that in 97.1% of cases, the laceral genu was lateral to the PVC, suggesting that the PVC corridor is a safer navigation route during surgeries, reducing the risk of ICA injury.
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Cryoablation is a well-established medical procedure for surgically treating atrial fibrillation. Cryothermal catheter therapy induces cellular necrosis by freezing the insides of pulmonary veins, with the goal of disrupting abnormal electrical heart signals. Nevertheless, tissue damage induced by cold temperatures may also lead to other complications after cardiac surgery.

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