α-tubulin detyrosination fine-tunes kinetochore-microtubule attachments.

Post-translational cycles of α-tubulin detyrosination and tyrosination generate microtubule diversity, the cellular functions of which remain largely unknown. Here we show that α-tubulin detyrosination regulates kinetochore-microtubule attachments to ensure normal chromosome oscillations and timely anaphase onset during mitosis. Remarkably, detyrosinated α-tubulin levels near kinetochore microtubule plus-ends depend on the direction of chromosome motion during metaphase.

Nanoparticles of nucleotide-free analogue of vitamin B formed in protein nanocarriers and their neuroprotective activity in vivo.

Recently, we have described the first supermolecular nanoentities of vitamin B derivative, viz. monocyano form of heptabutyl cobyrinate, unique nanoparticles with strong noncovalent intermolecular interactions, emerging optical and catalytic properties. Their nearest analogue, heptamethyl cobyrinate (ACCby), exhibits bioactivity.

Resonant generation of propagating second-harmonic spin waves in nano-waveguides.

Generation of second-harmonic waves is one of the universal nonlinear phenomena that have found numerous technical applications in many modern technologies, in particular, in photonics. This phenomenon also has great potential in the field of magnonics, which considers the use of spin waves in magnetic nanostructures to implement wave-based signal processing and computing. However, due to the strong frequency dependence of the phase velocity of spin waves, resonant phase-matched generation of second-harmonic spin waves has not yet been achieved in practice.

True amplification of spin waves in magnonic nano-waveguides.

Magnonic nano-devices exploit magnons - quanta of spin waves - to transmit and process information within a single integrated platform that has the potential to outperform traditional semiconductor-based electronics. The main missing cornerstone of this information nanotechnology is an efficient scheme for the amplification of propagating spin waves. The recent discovery of spin-orbit torque provided an elegant mechanism for propagation losses compensation.