Publications by authors named "V N Chinchilli"
Objectives: The Developmental Origins of Health and Disease (DOHaD) framework contends that chronic diseases are attributable to behavioral and environmental risks encountered during vital periods of fetal and childhood development. Clinical research investigating irritable bowel syndrome (IBS) largely focuses on adult risk factors, with emerging evidence of epigenetic contributions. Limited work considers potential childhood exposures.
View Article and Find Full Text PDFThis study examines the relationship between comorbid seizures and dementia among stroke patients using the 2017 Nationwide Inpatient Sample (NIS), the largest publicly available inpatient healthcare database in the United States. We analyzed data from 128,341 stroke patients, including those with ischemic and hemorrhagic strokes, to determine the prevalence of seizures and dementia, and the association between these conditions. Our findings reveal that 7.
View Article and Find Full Text PDFPsychometric properties of the revised internalized skin bias questionnaire.
J Eur Acad Dermatol Venereol
October 2024
Article Synopsis
- The study examines the psychological effects of skin diseases, which often lead to increased anxiety, depression, and a lower quality of life among patients due to internalized stigma related to their condition.
- The researchers refined the Internalized Skin Bias Questionnaire (ISBQ) to better assess skin-specific biases and evaluated its effectiveness through surveys involving dermatology experts and patients with skin conditions.
- Findings indicate that the revised version of the questionnaire (ISBQ-R) shows improved consistency and stronger correlations with other stigma measures, supporting its utility in understanding the psychological impact of skin diseases.
Article Synopsis
- The study investigated the rates of coinfections among patients with babesiosis, focusing on the relationship between these coinfections and severe health outcomes, including mortality.
- Researchers analyzed data from the TriNetX database from 2015 to 2022, identifying a 42% prevalence of coinfections primarily with an organism causing similar tick-borne diseases.
- Findings showed that 90-day mortality rates were actually lower in patients with coinfections compared to those with only babesiosis, highlighting a complex interplay between these infections and health outcomes.
Article Synopsis
- There has been an increase in early onset cancer rates (under 50) since 1995, particularly among adolescents and young adults (AYAs) aged 15-39, who tend to have different types of tumors compared to children and older adults.
- The study analyzed data from January 2016 to December 2021 using the SEER 22 database to assess age-adjusted incidence and mortality rates for various cancers by factors like sex, race, and geographic region.
- Overall cancer incidence and mortality rates remained stable during this period, with a decline in certain cancers (e.g., ependymoma and melanoma) and increases in others (e.g., gastrointestinal cancers), highlighting the unique cancer trends and health issues faced