GSAG:Ce scintillator: insights from yttrium admixture.

The GSAG:Ce scintillator represents a promising and cost-effective alternative to the expensive GGAG:Ce. Recent studies have attributed its low light yield to the thermal quenching effect. In this study, we employed the strategy of adding an yttrium (Y) admixture to the GSAG matrix to increase the thermal activation energy of thermal quenching.

Ho codoping of GGAG:Ce: a detailed analysis of acceleration of scintillation response and scintillation efficiency loss.

In this study, we investigate the effects of Ho codoping on the luminescence and scintillation properties of GGAG:Ce, with a particular focus on timing properties and scintillator efficiency. The research reveals that Ho codoping and subsequent resonant energy transfer from Ce to Ho can significantly reduce the 5d excited state decay time of Ce and shorten scintillation pulses of GGAG:Ce registered by using photomultipliers, although this reduces scintillator efficiency as well. The study presents a detailed analysis of the loss of scintillator efficiency due to Ho codoping, identifying the most significant loss pathways and estimating their impact.

On the Origin of the Light Yield Enhancement in Polymeric Composite Scintillators Loaded with Dense Nanoparticles.

Fast emitting polymeric scintillators are requested in advanced applications where high speed detectors with a large signal-to-noise ratio are needed. However, their low density implies a weak stopping power of high energy radiation and thus a limited light output and sensitivity. To enhance their performance, polymeric scintillators can be loaded with dense nanoparticles (NPs).

Immunogenicity and Safety of a Purified Vero Rabies Vaccine-Serum Free, Compared With 2 Licensed Vaccines, in a Simulated Rabies Post-Exposure Regimen in Healthy Adults in France: A Randomized, Controlled, Phase 3 Trial.

Background: A next-generation Vero cell rabies vaccine (PVRV-NG2) was developed using the same Pitman-Moore strain as in the licensed purified Vero cell vaccine (PVRV; Verorab) and the human diploid cell vaccine (HDCV; Imovax Rabies®).

Methods: This dual-center, modified, double-blind, phase 3 study evaluated the immunogenic non-inferiority and safety of PVRV-NG2 with and without concomitant intramuscular human rabies immunoglobulin (HRIG) versus PVRV + HRIG and HDCV + HRIG in a simulated post-exposure prophylaxis (PEP) regimen. Healthy adults ≥18 years old (N = 640) were randomized 3:1:1:1 to PVRV-NG2 + HRIG, PVRV + HRIG, HDCV + HRIG, or PVRV-NG2 alone (administered as single vaccine injections on days [D] 0, D3, D7, D14, and 28, with HRIG on D0 in applicable groups).

Charge Transfer and Charge Trapping Processes in Ca- or Al-Co-doped LuSiO and LuSiO Scintillators Activated by Pr or Ce Ions.

Lutetium oxyorthosilicate LuSiO (LSO) and pyrosilicate LuSiO (LPS) activated by Ce or Pr are known to be effective and fast scintillation materials for the detection of X-rays and γ-rays. Their performances can be further improved by co-doping with aliovalent ions. Herein, we investigate the Ce(Pr) → Ce(Pr) conversion and the formation of lattice defects stimulated by co-doping with Ca and Al in LSO and LPS powders prepared by the solid-state reaction process.