Publications by authors named "V Musiime"
Background: Iron deficiency is the most common nutritional deficiency in the world, but iron supplementation can increase risk of opportunistic infections, especially in children living with HIV. We aimed to assess the effect of supplemental iron on haemoglobin concentration in children living with HIV and mild-to-moderate anaemia in Uganda.
Methods: We did a double-blind, randomised, placebo-controlled trial of iron supplementation in children aged 6 months to 12 years living with HIV at two sites (ie, Kampala and Fort Portal, Uganda).
Article Synopsis
- - Refeeding syndrome is a serious complication that can occur in children suffering from severe acute malnutrition (SAM) when high-caloric feeding is resumed, particularly affecting electrolyte levels like phosphorus, potassium, and magnesium, with hypophosphatemia being a key indicator.
- - The study aimed to investigate how often refeeding syndrome occurs and what factors contribute to it during the transition phase of treatment for SAM in children aged 6 to 59 months at a hospital in Uganda.
- - Out of 150 children studied, 115 were analyzed, and 34.8% developed refeeding syndrome, highlighting that close monitoring of electrolyte levels is crucial during treatment of SAM to prevent this condition.
Article Synopsis
- Pneumonia is a major cause of death in children under 5, particularly among those with poor nutrition, making it important to identify body composition measures that can predict survival rates in these patients.* -
- This study analyzed 369 children aged 6-59 months with severe pneumonia in Uganda and Kenya, comparing indices of fat and muscle mass to see which was a better predictor of 6-month survival.* -
- Results showed that while Arm-Fat-Area had a comparable predictive ability for survival as Arm-Muscle-Area and Arm-Muscle-Circumference, none of these were significantly better than the measurement of Mid-Upper Arm Circumference (MUAC).*
This study examined the changes in the lipidome and associations with immune activation and cardiovascular disease markers in youth living with perinatally acquired HIV (YPHIV). The serum lipidome was measured in ART-treated YPHIV (n=100) and HIV- Ugandan children (n=98) Plasma markers of systemic inflammation, monocyte activation, gut integrity, T cell activation, as well as and common carotid artery intima-media thickness (IMT) and pulse wave velocity (PWV) were evaluated at baseline and 96 weeks. Overall, median age was 12 years,52% were females.
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