Publications by authors named "V Munteanu"
Bone loading is a crucial factor that constrains locomotor capacities of terrestrial tetrapods. To date, limb bone strains and stresses have been studied across various animals, with a primary emphasis on consistent bone loading in mammals of different sizes and variations in loading regimes across different clades and limb postures. However, the relationships between body size, limb posture and limb bone loading remain unclear in animals with non-parasagittally moving limbs, limiting our understanding of the evolution of limb functions in tetrapods.
View Article and Find Full Text PDFBackground And Aims: Non-small cell lung cancer (NSCLC) treatment is challenged by late detection and limited therapeutic options. Aberrant DNA methylation, a common epigenetic alteration in NSCLC, offers new therapeutic avenues. This study aims to evaluate the combined effects of 5-Azacytidine (5-Aza), an epigenetic modifier, and ionizing radiation (IR) on NSCLC, exploring the underlying molecular mechanisms and therapeutic potential.
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- The study compares a new minimally-invasive lymph node dissection technique for penile cancer (MILND) with the traditional open approach (OILND) to evaluate patient outcomes.
- Between 2016 and 2023, results showed that MILND had shorter operation times, shorter hospital stays, and fewer days with drainage compared to OILND, while also yielding similar or better lymph node results.
- Additionally, MILND led to a lower rate of major complications, suggesting it may enhance patient safety and recovery compared to the standard approach.
Pain is a subjective concept which is ever-present in the medical field. Health professionals are confronted with a variety of pain types and sources, as well as the challenge of managing a patient with acute or chronic suffering. An even bigger challenge is presented in the pediatric population, which often cannot quantify pain in a numerical scale like adults.
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- Data-driven computational analysis in biomedical research is hindered by poor sharing of research outputs, affecting the transparency and reproducibility of studies.
- An analysis of 453 manuscripts from 2016-2021 found that over half did not share analytical code, with only 10% organizing their code in a reproducible format.
- To improve reproducibility and promote scientific collaboration, the study emphasizes the need for better awareness and practices around sharing code and data in the biomedical field.