N-acetylcysteine inhibits proliferation, adhesion, migration and invasion of human bladder cancer cells.

Objective: Bladder cancer is not only a major public health and economically burden for the patients but also a major clinical impact for Thai urologists. The authors' aim was to study the anti-metastatic effect of N-acetylcysteine (NAC), one of the cheap, safe and widely used over-the-counter-drugs in Thailand, on the human bladder cancer cells.

Material And Method: Effects of NAC at various concentrations on the growth, adhesion, migration, and invasion of the human bladder cancer cell line were assessed in vitro.

Ureteral calculi during pregnancy: review of the management at Ramathibodi Hospital.

Objective: To review our experiences with diagnosis and management of symptomatic ureteral calculi complicating pregnancy.

Material And Method: Medical records of all pregnant patients documented with symptomatic ureteral calculi treated at the Division of Urology, Department of Surgery, Faculty of Medicine, Ramathibodi Hospital from 1990 to 2000 were reviewed. Presenting symptoms, diagnostic studies and management of ureteral stone were evaluated.

Ureterocalicostomy for reconstruction of complicated ureteropelvic junction obstruction.

Objective: To review our experience with ureterocalicostomy using the treatment of complicated ureteropelvic junction (UPJ) obstruction.

Material And Method: Medical records of all patients with complicated ureteropelvic junction obstruction treated by ureterocalicostomy from 1985 to 2000 were reviewed. Causes of UPJ obstruction, surgical techniques, peri-operative course and outcome were noted.

Penile fracture: long-term outcome of treatment.

Objective: Penile fracture is a rare injury, usually resulting from direct trauma to the erect penis during sexual intercourse. Immediate surgical treatment is the basis for the treatment of this injury due to the high rate of complications associated with delayed management. The aim of this study was to evaluate the clinical presentations, diagnostic methods, and outcomes of the treatment.

Mitrofanoff procedure incombination with enterocystoplasty for detrusor hyperreflexia with external sphincter dyssynergia: one-year experience of 12 cases.

Twelve patients with the mean age of 35 years who had undergone Mitrofanoff procedure incombination with enterocystoplasty between 1998-1999 were interviewed. All of the patients had suprasacral spinal cord injuries for the mean of 3.5 years from the accident to the operation and failure of medical treatment to suppress hyperreflexic bladder.