Publications by authors named "V Morgan"

Vigilance is a continuously altering state of cortical activation that influences cognition and behavior and is disrupted in multiple brain pathologies. Neuromodulatory nuclei in the brainstem and basal forebrain are implicated in arousal regulation and are key drivers of widespread neuronal activity and communication. However, it is unclear how their large-scale brain network architecture changes across dynamic variations in vigilance state (i.

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  • * Effective treatment for drug-resistant epilepsy is often surgical, relying heavily on imaging to identify abnormalities, though TEs are frequently missed on standard scans.
  • * This study explored a voxel-based morphometry (VBM) method to detect TEs in MRI scans, comparing its effectiveness to that of experienced neuroradiologists and epileptologists, revealing that VBM showed lower sensitivity and specificity but could still aid in improving detection and surgical outcomes.
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Background/objectives: This cross-national study focuses on adolescents who provide care and support to family members or significant others. Current evidence regarding their mental health and solutions to strengthen it is limited and mostly available in a few countries. The aim of this study is to evaluate the results of a primary prevention intervention for improving the mental health and well-being of adolescent young carers (AYCs) aged 15-17 years in six European countries.

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Introduction: Unicompartmental knee arthroplasty (UKA) has been shown to improve pain and function in appropriately selected patients. Limited data exists regarding outcomes and complication rates following UKA among octogenarians.

Methods: The PearlDiver Mariner database was queried for patients undergoing primary UKA between 2010-2022.

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  • The study explored how functional connectivity relates to seizure outcomes at different times after surgery in patients with temporal lobe epilepsy (TLE), focusing on those who underwent a specific surgical procedure known as selective amygdalohippocampectomy.
  • It compared the brain connectivity of patients who remained seizure-free after surgery to those who experienced seizures again, using resting-state fMRI scans taken pre- and post-surgery.
  • Results showed significant differences in brain network strength in specific areas for seizure-free patients, indicating that increased connectivity over time may contribute to better long-term seizure control.
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