RELATIONSHIP BETWEEN SARCOPENIA AND OSTEOPOROSIS IN NON-ALCOHOLIC FATTY LIVER DISEASE.

The article analyzes the scientific literature on the mechanisms of interaction of bones, muscles and adipose tissue in non-alcoholic fatty liver disease. Modern views on the mechanisms of sarcopenia, osteopenia and osteoporosis are highlighted. Interactions between muscles and bones involve the interaction of osteokines released from bones, muscle myokines, and cytokines, which trigger common signaling pathways leading to fibrosis, inflammation, or protein synthesis or degradation.

[Coagulation dystrophy--newly found kind of dystrophy].

It was shown that discovery by the author of the thrombin-plazmin system and establishment of its biological role consisting in maintenance of two fundamental opposite, internal and contradictory physiological processes--biological coagulation (cyto-histo-haemocoagulation) which is carried out by the thrombin subsystem and biological regeneration (cyto-histo-haemoregenerations) which is carried out by the plasmin subsystem, has given the chance to open the current mechanism of damage of structure and functions of human organs during DVS-syndrome. It has appeared that under intensification of biocoagulation, its damage is caused by the effect of thrombin which is present in all basic biological mediums--cytoplasm, interstitial connecting tissue and in blood and it causes primary direct coagulation (inherently degenerative) and secondary mediated coagulation (inherently dystrophic) damages, i.e.