Changes in the glycosaminoglycans distribution pattern in the human uterine cervix during pregnancy and labor.

The glycosaminoglycans distribution pattern of uterine cervix samples obtained from 42 women of reproductive age was determined by means of proteolytic digestion and subsequent chromatographic separation. The following glycosaminoglycans were detected: chondroitin 4- and 6-sulfates, dermatan sulfate, hyaluronate, chondroitin, and keratan sulfate. The connective tissue of the uterine cervix shows a characteristic distribution pattern with regard to glycosaminoglycans which does not correspond to that found in any other tissue studied so far.

A few factors contributing to the mechanical strength of collagen fibres.

A knowledge of the influence of several factors on the stability and properties of collagen and preparations thereof precedes their industrial application. The results of such a study are reported in this paper. The mechanical properties of skin samples vary significantly with location and direction of cutting.