Publications by authors named "V Mattioni Marchetti"

The concentrations of fecal and serum bile acids (BAs) are known to be altered in human patients with chronic liver diseases (CLDs), especially those with biliary tract involvement (BTD). Scarce literature is available regarding fecal BA modifications during canine CLDs. This study aimed to evaluate fecal BAs in canine CLDs according to different clinical and clinicopathological variables.

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(1) Background: Ultrasound attenuation imaging (ATI) is an innovative technique that allows for the evaluation of the degree of lipid infiltration of the liver parenchyma in a simple and non-invasive way. The objective of this study was to verify the applicability of the ATI method in the evaluation of hyperlipidemia. (2) Methods: This study included 53 dogs between January 2021 and December 2022, of which 21 were healthy (A) and 32 had hyperlipidemia (B).

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Article Synopsis
  • - Monitoring antimicrobial use is vital for understanding prescribing trends and forming effective stewardship programs to combat resistance; this study focuses on the veterinary practices at the University of Pisa.
  • - The study analyzed antimicrobial prescriptions for 1,164 non-surgical cats in 2021 and 2022, revealing that amoxicillin-clavulanic acid was most used in internal medicine while ampicillin dominated in intensive care, with 25% being critically important antimicrobials.
  • - Results indicated that most antimicrobials were prescribed for urinary, gastroenteric, respiratory, and integumentary conditions, but only 11% were backed by susceptibility tests, highlighting the need for improvements in targeted therapy and awareness of the broader effects of antimicrobial
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Alteration in the gut microbiome in human patients with chronic liver disease is a well-known pathophysiological mechanism. Therefore, it represents both a diagnostic and therapeutical target. Intestinal dysbiosis has also been identified in dogs with chronic liver disease, but clinical trials evaluating the effectiveness of synbiotic administration are lacking.

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