Publications by authors named "V Matthews"

Food insecurity disproportionately impacts Indigenous peoples, leading to significant health disparities. Indigenous peoples globally share a deep and interconnected relationship to their lands, waterways and seas that ensures optimum health, and cultural, spiritual, social and emotional wellbeing. However, food security definitions and assessment frameworks in research and policy predominantly stem from capitalist and colonial food system values.

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Background: Atrial fibrillation (AF) is associated with significant morbidity/mortality. AF-ablation is an increasingly used treatment. Currently, first-time AF-ablation success is 40-80% at 1-year, depending on individual factors.

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Background: Indigenous communities worldwide lead calls for all evaluations of research, programmes and policies affecting their communities to reflect the values, priorities and perspectives of the Indigenous peoples and communities involved. Tools, such as the Quality Appraisal Tool (QAT), are available to assess research quality through an Indigenous cultural lens. Good evaluation requires that evaluation efforts be evaluated.

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Article Synopsis
  • Hyperactivation of the sympathetic nervous system (SNS) is associated with obesity, hypertension, and type 2 diabetes, and leads to increased norepinephrine (NE) levels which may affect sodium-glucose transport proteins.
  • The study investigates the expression of sodium-dependent glucose cotransporters SGLT1 and SGLT2 in skeletal muscle, finding that NE significantly elevates SGLT1 levels in skeletal muscle cells.
  • Treatment with the dual inhibitor Sotagliflozin in neurogenically hypertensive mice effectively reduced blood pressure, suggesting that targeting SGLT1 could help manage conditions driven by high SNS activity, warranting further clinical studies.
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Scope: Higher intake of cruciferous and allium vegetables is associated with lower cardiometabolic risk. Little research has investigated the cardiometabolic effects of S-methyl cysteine sulfoxide (SMCSO), found abundant in these vegetables. This study hypothesizes that SMCSO will blunt development of metabolic syndrome features in mice fed high-fat feed.

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