Publications by authors named "V Matias"

Objective: To evaluate the pregabalins adjuvant effect in patients with carpal tunnel syndrome (CTS) surgically treated, analyzing postoperative pain and the incidence of complex regional pain syndrome (CRPS).

Methods: Outpatient surgical candidates with CTS were selected and followed for 12 months, divided into three groups. The Control Group received a placebo, the Pregabalin 75 mg Group received a daily dose, and the Pregabalin 150 mg Group received a daily dose of the medication.

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Article Synopsis
  • The study investigates how the immune response to respiratory syncytial virus (RSV) infection may lead to severe hypoxemia in children, affecting their ability to exchange oxygen and carbon dioxide effectively.
  • Researchers analyzed blood samples from 121 RSV-infected children and discovered that a specific inflammatory gene was overexpressed in those with severe hypoxemia, while multiple antiviral genes were underexpressed.
  • The findings suggest that an imbalance between inflammation and antiviral defense mechanisms could play a significant role in the severity of RSV-related respiratory issues in children.
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Article Synopsis
  • * Participants were divided into three groups: one received a placebo, another received 75mg of pregabalin daily, and the third received 150mg daily, with their pain and progress monitored over 12 months.
  • * Results indicated that pregabalin did not significantly improve pain relief or reduce the incidence of CRPS in CTS surgical patients, suggesting it may not be a helpful addition to their treatment plan.
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Objectives: We aimed to analyze whether the expression of inflammatory and antiviral genes in respiratory syncytial virus (RSV)-infected infants' peripheral blood is associated with bronchiolitis progression.

Methods: We conducted a prospective study on 117 infants between 2015 and 2023. The expression levels of nine genes were quantified by quantitative polymerase chain reaction.

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Group A Rotavirus, Human Astrovirus, and Norovirus (RVA, HAstV, and NoV) are recognized as the major causative agents of acute gastroenteritis in children and adults worldwide. The aim of this study was to determine the prevalence and molecular epidemiology of RVA, HAstV, and NoV in wastewater from three cities in Uruguay. Thirty-six samples from Bella Unión, Salto, and Fray Bentos cities were analyzed using quantitative and qualitative PCR.

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