Publications by authors named "V Martiadis"
Introduction/objective: Data on long-term treatment with Esketamine Nasal Spray (ESKNS) in real-world patients with treatment resistant depression (TRD) is scarce. The primary aim of the study is to evaluate the effectiveness and tolerability of ESK-NS treatment at 6 and 12-month follow-ups.
Methods: This is part of an observational, retrospective, multicentric Italian study (REAL-ESK study).
Schizophrenia, a highly complex psychiatric disorder, presents significant challenges in diagnosis and treatment due to its multifaceted neurobiological underpinnings. Recent advancements in functional magnetic resonance imaging (fMRI) and artificial intelligence (AI) have revolutionized the understanding and management of this condition. This manuscript explores how the integration of these technologies has unveiled key insights into schizophrenia's structural and functional neural anomalies.
View Article and Find Full Text PDFObsessive-compulsive disorder (OCD) is a common and debilitating psychiatric disorder with an approximate incidence of 2.5% in the general population. Serotonin reuptake inhibitors (SRIs) are considered the first line of pharmacological treatment but up to 50% of patients fail to achieve clinical remission or response.
View Article and Find Full Text PDFObesity and weight gain represent a challenging issue in people suffering from schizophrenia and other severe mental illnesses (SMI). Most of clinical guidelines for the management of overweight and obesity in people with SMI share a stepwise approach starting with more conservative interventions, with diet, physical activity, lifestyle coaching and behavioral modifications. The aim of this study was to evaluate the effectiveness of a group weight management program in a real-world outpatient Italian setting.
View Article and Find Full Text PDFArticle Synopsis
- Treatment-Resistant Depression (TRD) affects about 30% of people with Major Depressive Disorder, and a new nasal spray called Esketamine (ESK-NS) has been approved to help treat it when combined with certain medications.
- Researchers wanted to see if combining Vortioxetine, another antidepressant, with ESK-NS was just as good or better than the usual treatment.
- The results showed that the Vortioxetine and ESK-NS combo worked well to reduce depression and had fewer side effects, suggesting it could be a better option, but more research is needed to be sure.