Publications by authors named "V Manja"
Background: Deprescribing antihypertensives is of growing interest in geriatric medicine, yet the impact on functional status is unknown. We emulated a target trial of deprescribing antihypertensive medications compared with continued use on functional status measured by activities of daily living (ADL) in a long-term care population.
Methods: We included 12,238 Veteran Affairs long-term care residents age 65+ who had a stay ≥ 12 weeks between 2006 and 2019.
Article Synopsis
- The study examined antihypertensive treatment changes among long-term care residents, focusing on patterns and factors influencing these changes over a period from 2006 to 2019.
- Out of nearly 25,000 nursing home residents aged 65 and older, over 68% experienced at least one change in their antihypertensive medications within the first six months of admission.
- Key findings included that treatment changes were more frequent in those with better physical or cognitive health, with different triggers for deprescribing (like low blood pressure) and intensification (such as high blood pressure and cardiovascular events).
Background: Although methamphetamine use associated heart failure (MU-HF) is increasing, data on its clinical course are limited due to a preponderance of single center studies and significant heterogeneity in the definition of MU-HF in the published literature. Our objective was to evaluate left ventricular ejection fraction (LVEF) distribution, methamphetamine use treatment engagement and postdischarge healthcare utilization among Veterans with heart failure hospitalization in the department of Veterans Affairs (VA) medical centers for MU-HF versus HF not associated with methamphetamine use (other-HF).
Methods: Observational study including a cohort of Veterans with a first heart failure hospitalization during 2007 - 2020 using data in the VA Corporate Data Warehouse.