Adapting a Longitudinal Structured Program to Enhance Research Skills in Undergraduate Medical Students: A Key Advancement in Competency-Based Medical Education.

Background: Abundant literature signifies the imperative role of evidence-based research in the health sector which underpins the importance of training medical graduates in research skills early in their medical journey. Low awareness, less knowledge, and minimal practical involvement of undergraduates (UGs) in research have been identified all over India. The lack of structured delivery of research curriculum in the UG period has been the basis of uptaking this project with the aim of developing research competency in medical UGs.

Comparative Effects of Kapalbhati and Slow Deep Breathing on Heart Rate Variability: Mechanistic Insights into Sympathetic and Parasympathetic Dominance.

The autonomic nervous system governs rhythmic fluctuations in blood pressure and heart rate, which are influenced by breathing patterns. This study aims to explore how different breathing techniques, specifically Kapalbhati (fast-paced breathing) and Slow Deep Breathing (SDB), affect heart rate variability (HRV). This study was conducted in the Department of Physiology and AYUSH at AIIMS Bhopal, India and duration was 2 (Two) months from May 2021 to June 2021 This quasi-experimental study involved 60 participants divided into two groups: Kapalbhati and SDB.

Comparative Neurodynamic Analysis of Spinal Energy Enhancement in Experienced Yoga Practitioners Using Various Breathing Techniques.

Introduction:  Yoga practices emphasize spinal energy's role in physical, mental, and spiritual well-being, suggesting specific techniques that can enhance energy flow along the spine. Modern research aims to validate these claims and understand the mechanisms behind these effects, potentially integrating them into contemporary healthcare models. This study explores the relationship between yoga breathing techniques, spinal energy dynamics, and health based on yoga philosophy and bioenergetics.

Demonstration of Membrane Transport of Histidine using Goat Intestinal Inverted Sacs: An Experiential Pedagogical Tool for Undergraduates.

Histidine is an essential amino acid that is also a precursor for metabolites implicated in the immune system, pulmonary ventilation, and vascular circulation. Absorption of dietary histidine relies largely on the sodium-coupled neutral amino acid transport by the Broad neutral amino acid transporter (BAT) present on the apical membrane of the enterocyte. Here, we demonstrate the absorption of histidine by the intestinal villus enterocytes from the lumen using goat jejunal inverted sacs.

Cross-Coupling of NHC/CAAC-Based Carbodicarbene: Synthesis of Electron-Deficient Diradicaloids.

Herein, we report nickel(0)-catalyzed cross-coupling reactions of NHC/CAAC-based carbodicarbene (NHC = -heterocyclic carbene and CAAC = cyclic(alkyl)(amino)carbene) with different aryl chlorides, bromides, and iodides. The resulting aryl-substituted cationic carbodicarbene derivatives are prone to one-electron oxidation yielding radical-dications, which, depending on the aryl motif employed, follow different modes of radical-radical dimerization and constitute an entry point to carbon/nitrogen- and nitrogen/nitrogen-centered diradicaloids. Subsequently, this coupling strategy was strategically applied to the synthesis of -phenylene- and ,-biphenylene-bridged carbon/carbon-centered electron-deficient diradicaloids.