Publications by authors named "V Magnusson"

Background: Many prehospital emergency patients receive suboptimal treatment for their moderate to severe pain. Various factors may contribute. We aim to systematically review literature pertaining to prehospital emergency adult patients with acute pain and the pain-reducing effects, adverse events (AEs), and safety issues associated with inhaled analgetic agents compared with other prehospital analgesic agents.

View Article and Find Full Text PDF

Background: Helicopter emergency services (HEMS) are widely used to bring medical assistance to individuals that cannot be reached by other means or individuals that have time-critical medical conditions, such as chest pain, stroke or severe trauma. It is a very expensive resource whose use and importance depends on local conditions. The aim of this study was to describe flight and patient characteristics in all HEMS flights done in Iceland, a geographically isolated, mountainous and sparsely populated country, over a 5-year course.

View Article and Find Full Text PDF
Article Synopsis
  • Long-QT syndrome (LQTS) is a heart condition that can cause sudden cardiac death and is mainly linked to rare genetic variants in specific genes.
  • A study in Iceland identified 12 genetic variants associated with prolonged QTc intervals, revealing a higher carrier frequency than previously thought.
  • The study concluded that certain variants, particularly p.Tyr315Cys and p.Leu273Phe, lead to more severe outcomes, which can inform better risk assessment and treatment strategies for patients with QTc prolongation.
View Article and Find Full Text PDF

Introduction: Acute pain is a frequent symptom among patients in the pre-hospital setting, and opioids are the most widely used class of drugs for the relief of pain in these patients. However, the evidence base for opioid use in this setting appears to be weak. The aim of this systematic review was to explore the efficacy and safety of opioid analgesics in the pre-hospital setting and to assess potential alternative therapies.

View Article and Find Full Text PDF

Background: Few publications have addressed prehospital use of ketamine in analgesic doses. We aimed to assess the effect and safety profile of ketamine compared with other analgesic drugs (or no drug) in adult prehospital patients with acute pain.

Methods: A systematic review of clinical trials assessing prehospital administration of ketamine in analgesic doses compared with other analgesic drugs or no analgesic treatment in adults.

View Article and Find Full Text PDF