[Modeling of linoleyl hydroxamic acid influence on lipoxygenases in vitro].

5-Lipoxygenase (5-LO) (1.13.11.

[Phosphorus-containing inhibitors of penicillin acylase. 4. Irreversible inhibition of penicillin acylase from Escherichia coli by monoaryl esters of benzylphosphonic acid].

Monoaryl of benzylphosphonic acid have been synthesized and studied as the inhibitors of penicillin acylase. These compounds were found to be effective and selective irreversible inhibitors of the enzyme. The kinetic parameters of enzyme inactivation are determined, and possible mechanism of the inhibition is discussed.

[Inhibition of penicillin acylase from Escherichia coli by benzylalkylketones and benzylalkylcarbinols].

A number of benzylalkylketones and benzylalkylcarbinols have been synthesized as non-hydrolizable substrate analogues of penicillin acylase (EC 3.5.1.

[Phosphorus-containing inhibitors of penicillin acylase. 3. Inhibition of Escherichia coli penicillin acylase by phosphonate analogs of substrates].

Phosphonic analogues of penicillin acylase substrates are found to be selective reversible competitive inhibitors of the enzyme from E. coli (EC 3.5.

[Phosphorus-containing inhibitors of penicillin acylase. 2. Design, synthesis and study of the hydrolytic stability of phosphonic acid derivatives as potential inhibitors of penicillin acylase].

Phosphonate and phosphonoamidate derivatives of benzylphosphonic acids were synthesized as potential inhibitors of penicillin acylase (EC 3.5.1.