[THE HISTORY OF DEPARTMENT OF FACULTY THERAPY, AT THE VORONEZH HIGHER EDUCATION INSTITUTION (ON THE OCCASION OF THE CENTENARY ANNIVERSARY OF N.N. BURDENKO VORONEZH STATE MEDICAL UNIVERSITY)].

The article is devoted to the history of the Department of Faculty Therapy, N.N. Burdenko Voronezh State Medical University.

[Clinical manifestations of asthma during combination therapy using ceruloplasmin].

Aim: To estimate the time course of clinical changes in patients with asthma during combination therapy using ceruloplasmin (CP).

Materials And Methods: A total of 92 asthmatic patients were examined. Their medical history data were collected; external lung function testing and clinical, laboratory, and instrumental examinations, involving the determination of the indicators of lipid peroxidation (LPO) (malonic dialdehyde (MDA), methemoglobin, carboxyhemoglobin) and the antioxidant system (superoxide dismutase (COD), sulfhydryl groups), were performed in all the patients over time.

[CHRONIC OBSTRUCTIVE PULMONARY DISEASE AND ANEMIA: CLINICAL MANIFESTATIONS AND THERAPEUTIC STRATEGY].

Unlabelled: Anemia refers to manifestations of systemic inflammation in chronic obstructive pulmonary disease (COPD) and a factor aggravating the disease.

Objective: To study gender characteristics of anemia in patients with COPD, to increase the effectiveness of treatment through the use of pharmacological agents erythropoietin and enteral iron.

Materials And Methods: The paper presents clinical data on 74 patients with stage II/III COPD and anemia along with results of the treatment of 49 patients who received standard therapy in addition to epoetin and Sorbiferdurules.

[ANTIOXIDANT THERAPY OF BRONCHIAL ASTHMA].

This paper summarizes results of the investigations into the influence of antioxidants on the clinical picture of bronchial asthma. This disease is known to be accompanied by hyperactivation of lipid peroxidation. The use of antioxidants permits to correct free-radical oxidation (peroxidation) and enhances effectiveness of control over clinical symptoms.

[PROINFLAMMATORY CYTOKINES IN COMBINATION OF CORONARY HEART DISEASE AND CHRONIC OBSTRUCTIVE PULMONARY DISEASE].

Chronic obstructive pulmonary disease and coronary heart disease frequently occur in combination. Systemic inflammation concomitant with protracted COPD is the pathogenetic mechanism of CHD. High concentration of the markers of systemic inflammation is associated with deterioration of atherosclerosis, its complications, and CHD progression.