Publications by authors named "V M Polivanov"
Background/objectives: Pulmonary fibrosis (PF) results in a progressive decline of lung function due to scarring. Drugs are among the most common causes of PF. The objective of our study was to reveal the structure of drugs involved in PF development.
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- Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare but severe skin reactions to medications, and analyzing a national database provides valuable insights into their occurrence.
- A study was conducted using reports from the Russian National Pharmacovigilance database between April 2019 and December 2023, focusing on demographic data and the drugs implicated in SJS and TEN cases.
- Out of 170 reports, 32.9% were SJS, 67.1% were TEN, with a notable number of cases in both pediatric and elderly populations; the most common drugs linked to these conditions included lamotrigine, ibuprofen, and ceftriaxone.
(1) Background: National health system databases represent an important source of information about the epidemiology of adverse drug reactions including drug-induced allergy and anaphylaxis. Analysis of such databases may enhance the knowledge of healthcare professionals regarding the problem of drug-induced anaphylaxis. (2) Methods: A retrospective descriptive analysis was carried out of spontaneous reports (SRs) with data on drug-induced anaphylaxis (SRsAs) extracted from the Russian National Pharmacovigilance database (analyzed period 2 April 2019-21 June 2023).
View Article and Find Full Text PDFBackground: Comprehensive analysis of all available data in spontaneous reports (SRs) can reveal previously unidentified medication errors (MEs).
Methods: To detect MEs, we performed a retrospective analysis of SRs submitted to the Russian pharmacovigilance database in the period from January 01, 2012, to August 01, 2014. This study evaluated SRs of cases where beta-lactam antibiotics were the suspected drug.
The discovery in migrating birds of influenzaviruses and the demonstration of relationships between strains found in man and in birds show the importance of these investigations for influenzavirus ecology. Investigation of birds in the far-east regions of the USSR is particularly important as many of them migrate to South-East Asia and China, the regions from which human influenza pandemics seem to originate. A total of 262 bird sera from these regions were titrated by the HI method with 20 different influenzavirus antigens (5 human, 2 equine, 1 swine, and 12 avian influenzaviruses).
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