Publications by authors named "V M Palma"
In the tissue regeneration field, stem cell transplantation represents a promising therapeutic strategy. To favor their implantation, proliferation and differentiation need to be controlled. Several studies have demonstrated that stem cell fate can be controlled by applying continuous electric field stimulation.
View Article and Find Full Text PDFArticle Synopsis
- Sustained adrenergic overload can lead to harmful changes in the heart, characterized by oxidative stress, which can worsen heart function.
- Boldine (BOL), an antioxidant, was tested for its potential to protect the heart from damage caused by isoproterenol (ISO) in a rat study.
- Results showed that BOL significantly reduced heart enlargement and improved oxidative stress markers compared to ISO alone, suggesting it could be a beneficial treatment for adverse cardiac changes.
Psoriasis is a chronic inflammatory skin disease characterized by periods of remission and relapse. In this pathology, keratinocytes, dendritic cells, and different subpopulations of T cells are critical to developing psoriatic lesions. Although current treatments can reduce symptoms, they reappear in previously injured areas months after stopping treatment.
View Article and Find Full Text PDFPulmonary hypertension (PH) associated with heart failure with preserved ejection fraction (PH-HFpEF) represents a frequent form of PH related to left ventricular dysfunction. The pathophysiology of PH-HFpEF is intricate, and varied and includes vascular, cardiac, and pulmonary factors that contribute synergistically to developing this clinical syndrome. Improved knowledge of the pathophysiology of PH-HFpEF has paved the way for the use of new drugs such as angiotensin receptor neprilysin inhibitors (ARNIs), non-steroidal mineral corticoid receptor antagonist (nsMRA), sodium-glucose cotransporter inhibitors (SGLT2is), levosimendan, and glucagon-like peptide 1 (GLP-1) agonists.
View Article and Find Full Text PDFAim: Parents' perspectives on their child's obesity (BMI >IOTF-30) management are essential to ensure positive outcomes. This study explored parents' experiences in managing their children's obesity and investigated the sociocultural and environmental factors influencing such management on Reunion Island, a French overseas department in the Indian Ocean.
Methods: This qualitative study used a general inductive analysis approach.