[Effects of enterosorption on the activity of natural-resistance humoral factors in patients with burns].

The data suggesting the enterosorbent influence on the activity of proteolysis inhibitors and arginase, on the fibrin-fibrinogen and fibronectin decay products content, blood serum toxin fixating activity of injured with the burns were presented. The dependence of expression of mentioned indexes changes from the trauma severity in acute burn disease period was shown. The enterosgel application promotes the lowering of dystrophic degree severity, alike the hepar and fixed macrophage system load, the investigated indexes normalization acceleration, and patients condition improvement.

[The effect of antiprotein plasma on humoral resistance in children with severe burns].

In severely burned children, depending on severity of injury, the anti-triptic activity of blood serum, alpha 2-macroglobulin level, fibronectin, activity of an arginase decrease at the acute period of toxemia and septic toxemia. The content of the products of fibrin-fibrinogen degradation increases considerably. Alteration of the indices studied is of informative value and is associated with dynamics of the toxic syndrome development.

[Efficacy of the use of a stabilized alpha2-macroglobulin concentrate in experimental burns].

The effectiveness of the use of a stabilized composition of alpha 2-macroglobulin concentrate obtained from fraction III of plasma proteins according to Cohn in burn disease in the experiment on guinea pigs was studied. Under the influence of intraabdominal administration for 4 days of alpha 2-macroglobulin concentrate with a stabilizer, healing of the burn wounds, normalization of a state of the animals occurred 2 times more rapidly than in control ones, activity of acid proteinases restored by day 5 (in control--by day 14) due to increase in activity of proteolytic enzyme inhibitors.

[Effect of sorption detoxification in severe burns on the development of cell-mediated reactions in the vascular and extravascular phases of inflammation].

In combined use of general and local sorption detoxication in 30 patients with severe burns, the pronounced antiinflammatory action is caused by redistribution of neutrophilic granulocytes with different activity of myeloperoxidase systems, decrease in lesion of a vascular wall and development of the perfect cellular reactions into extravascular phase of inflammation. The area of deep burn wounds reduced 2.8-fold when compared with that in patients, in whom no sorption methods were used.