Publications by authors named "V M Kokorin"

Insomnia is a serious and widespread public health problem, but is often undetected and patients do not receive needed treatment. Insomnia is often comorbid with other diseases and conditions, such as arterial hypertension, type 2 diabetes mellitus, pain syndromes, anxiety and depressive disorders, etc. A separate problem is drug-induced insomnia, when patients develop symptoms due to other diseases treatments.

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Article Synopsis
  • - The document reviews recent studies and international guidelines to provide updated recommendations for internists managing acute heart failure (AHF) in complex patient scenarios.
  • - Seven key clinical questions (PICOs) were identified regarding diagnosis and treatment, emphasizing the importance of echocardiography and natriuretic peptide evaluations, along with other diagnostic tools.
  • - A total of 51 tailored recommendations were developed to address treatment strategies and improve outcomes for AHF patients, including options for managing low blood pressure and preventing rehospitalization.
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Sleep disorders are becoming increasingly important due to the high comorbidity with other diseases and a significant impact on the patient's quality of life. Insomnia is the most common sleep disorder both in the general population and in patients with multimorbid pathology. Its prevalence in the general population is 6-15%, while in patients with somatic diseases it increases up to 20-40% and can reach 90% in patients with comorbid mental disorders.

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Article Synopsis
  • This document reviews recent trials and updates international clinical practice guidelines (CPGs) to help doctors make decisions about diagnosing and treating acute pulmonary embolism (PE) in complex cases.
  • The authors identified five specific clinical issues related to PE and evaluated existing CPGs to create tailored recommendations, such as preferred diagnostic methods and treatment protocols depending on patient conditions like pregnancy.
  • Ultimately, the document provides 35 endorsed recommendations, aiming to simplify the decision-making process for clinicians managing patients with acute PE.
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