Publications by authors named "V M Ellis"
Article Synopsis
- Triatoma sanguisuga, the most common triatomine bug in the US, carries the parasite Trypanosoma cruzi, responsible for Chagas disease, although diagnoses are rare in the country.
- The study presented the first complete genome sequence of T. sanguisuga, obtained from a specimen in Delaware, revealing a genome size of 1.162 Gbp with high assembly quality, evidenced by a 99.1% BUSCO score.
- This genomic information can enhance understanding of triatomine bugs in colder climates and support public health initiatives for managing vector-borne diseases.
Article Synopsis
- The text discusses the most common triatomine bug species in the US, which can transmit Chagas disease, highlighting its public health relevance despite few cases being diagnosed.
- Researchers sequenced the first complete genome of this species using DNA from a specimen found in Delaware, achieving a size of 1.162 Gbp with a high completeness score.
- This genome is the first for a North American triatomine species and will aid in studying its biology and role in disease transmission, potentially enhancing disease management and public health efforts.
Interactions among pathogen genotypes that vary in host specificity may affect overall transmission dynamics in multi-host systems. , a bacterium that causes Lyme disease, is typically transmitted among wildlife by ticks. Despite the existence of many alleles of 's outer surface protein C () gene, most human infections are caused by a small number of alleles ["human infectious alleles" (HIAs)], suggesting variation in host specificity associated with .
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