Combined oral and vaginal treatment of severe vulvovaginitis during childhood.

Study Objective: To evaluate the efficacy and safety of combined oral and vaginal administration of antibiotics.

Design: Treatment and follow-up examination of 54 cases of severe vulvovaginitis.

Setting: Division of Pediatric and Adolescent' Gynecology, Second Department of Obstetrics and Gynecology, University of Athens, Greece.

Untreated cervical infections, chorioamnionitis and prematurity.

Objective: To examine the relationship of endocervical pathogens and cervicitis with the development of chorioamnionitis, premature rupture of membranes (PROM) and prematurity.

Methods: Three groups of pregnant women were included in the study: group A, controls with no evidence of cervicitis; group B, women with cervicitis due to pathogenic bacteria, who had been treated; and group C, women with untreated cervicitis who had not followed the prescribed therapy. Endocervical samples were cultured and aerobic and anaerobic bacteria isolated to examine the correlation of cervicitis with chorioamnionitis, PROM and prematurity.

Chronic or recurrent vaginal candidosis: short-term treatment and prophylaxis with itraconazole.

Twenty-one women (mean age, 35.3 years) with 2 to 4 episodes of vaginal candidosis in the last 6 months were included in the study to evaluate the efficacy and safety of itraconazole as short-term, as well as prophylactic, treatment of chronic candidosis. After clinical evaluation and laboratory confirmation of candidosis, 200 mg of itraconazole were given orally for 3 days.