Publications by authors named "V Likhvantsev"

Objective: To systematically evaluate the impact of the Trendelenburg position on hemodynamic parameters in adult patients.

Design: Systematic literature review and meta-analysis using PubMed and Medline.

Setting: All prospective interventional studies comparing the hemodynamic characteristics of patients in the horizontal supine position and Trendelenburg position.

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Article Synopsis
  • Machine learning (ML) is increasingly important for predicting sepsis, a critical condition where timely intervention is crucial; this study explores the effectiveness of ML models in clinical settings.
  • Researchers analyzed 73 studies involving nearly 458,000 patients and found that ML models, particularly Neural Networks and Decision Trees, performed better than traditional scoring systems, achieving a pooled AUC of 0.825.
  • The study emphasizes the need for standardized practices in reporting and validating ML models to enhance their clinical application and effectiveness in predicting sepsis across diverse patient populations.
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Background: Breast cancer (BC) mortality primarily stems from metastases rather than the primary tumor itself. Perioperative stress, encompassing both surgical and anesthetic factors, profoundly impacts the immune system, leading to alterations in neuroendocrine pathways and immune functions, potentially facilitating tumor progression and metastasis. Understanding the immunomodulatory effects of different anesthesia techniques is crucial for optimizing perioperative care in patients with BC.

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The prevailing model for understanding chronic critical illness is a biphasic model, suggesting phases of acute and chronic critical conditions. A major challenge within this model is the difficulty in determining the timing of the process chronicity. It is likely that the triad of symptoms (inflammation, catabolism, and immunosuppression [ICIS]) could be associated with this particular point.

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Background: Postoperative agitation is common after non-cardiac surgery. It is associated with postoperative delirium and cognitive dysfunction, leading to prolonged hospital stay and delayed social readjustment. Prevention and treatment strategies are lacking.

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