[Karyometry of BBN-induced precancerosis of the urothelium : An experimental analysis].

Background: The morphology of experimental precancerous lesions of the urinary bladder has been interpreted quite differently by various authors.

Objectives: The aim of this investigation was to quantify these lesions by karyometry and, thus, to gain a more reliable understanding of the process.

Materials And Methods: A total of 60 Wistar rats were fed with N‑butyl-N-(4-hydroxybutyl)nitrosamine (BBN) at a concentration of 0.