NOTCH4 gene promoter polymorphism is associated with the age of onset in schizophrenia.

Objectives: The NOTCH4 gene has a promoter polymor-phism at position -25, which leads to the three genotypes TT, CT and CC. These have been suggested to present a novel independent genetic risk factor for schizophrenia. We conducted a prospective case-control study to explore the impact of NOTCH4 T-25C polymorphism on the factors associated with schizophrenia.

The reliability of compliance assessments performed by doctors and patients during neuroleptic treatment: a comparison of compliance ratings.

Objective: To compare compliance assessments made by doctors and patients during neuroleptic drug treatment and to detect any variables explaining the discrepancies between their ratings.

Method: Compliance reports regarding neuroleptic medication were collected from 100 in-patients and out-patients and from their doctors. Re-ratings were performed after 1-2 weeks.

Position of teeth on the edentulous atrophic maxilla.

For prosthetic treatment of strongly atrophic alveolar wall, some biometric methods have been developed. The measurements taken from plaster cast models of 230 edentulous, average 29.9 years, and 125 dentulous post-menopausal women were correlated.

Attitudes towards neuroleptic treatment: reliability and validity of the attitudes towards neuroleptic treatment (ANT) questionnaire.

Non-compliance problems may rise to 50% among patients undergoing neuroleptic treatment. There are no direct measures available to predict compliance, if previous non-compliance is not taken into account. Attitudes towards neuroleptic treatment and insight into psychotic symptoms may vary during the course of the treatment process.

Relationship between body mass index and the remaining alveolar ridge.

Severe residual ridge resorption may occur in individuals with either high or low mineral density in the skeleton. Heavy individuals with a heavy skeleton and a large percentage of fat in the body are less predisposed to osteoporosis than small individuals are. In addition, the jaws of heavy subjects are probably more massive and thick than the jaws of smaller individuals.