Conception and Optimization of Extraction-Free Loop-Mediated Isothermal Amplification Detection of Dry Rot Fungus .

The use of nucleic acid-based detection tools for microorganisms and fungi has become a gold standard. This is particularly the case for wood-decaying fungi like which are hard to discriminate based on macroscopic and microscopic observations. This dry rot is important to detect as it is particularly destructive in an infested building, which requires immediate action to prevent spreading and significant damage to structural elements.

Manganese-enriched CsPbCl perovskite nanocrystals for self-assembled supercrystals.

The self-assembly of CsPbCl perovskite nanocrystals and their Mn-enriched analogs into supercrystals is reported. Increasing Mn content in the nanocrystals leads to formation of larger, increasingly uniform cubic supercrystals that eventually become rod-like with higher photoluminescence quantum yields.

Associating sensory cues with incoming seizures: developing an animal model of auras.

For patients with epilepsy, one of the biggest problems is the unpredictability of the time when the next seizure will occur. Interestingly, some epileptic patients experience a sensory sensation preceding seizures, called aura, which helps them move to safety before a seizure. Here, we describe the development of the first animal model of auras, which could allow for a more detailed study of this phenomenon.

Impact of time intervals on drug efficacy and phenotypic outcomes in acute respiratory distress syndrome in mice.

Acute respiratory distress syndrome is a severe lung condition resulting from various causes, with life-threatening consequences that necessitate intensive care. The phenomenon can be modeled in preclinical models, notably through the use of lipopolysaccharide (LPS) instillation in mice. The phenotype induced closely recapitulates the human syndrome, including pulmonary edema, leukocyte infiltration, acute inflammation, impaired pulmonary function, and histological damage.