[Ways of optimization in teaching of internal diseases in a medical institute].

A method of practical clinical games (PCG) performing is represented. For the PCG themes the extreme and urgent situations requiring the doctors of various specialities (especially on the cardiology and hematology cycles) are selected. A model of specific clinical situation, where students play roles, corresponding to the duties of speciality under conditions, maximally approximating to reality, is reproduced.

[Changes in the neuronal activity of the ventrolateral thalamic nucleus and in the motor components of an instrumental reaction in cats following the systemic administration of N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)].

Activity of ventrolateral thalamic neurons during performance of instrumental reaction was studied in four cats before (81 neurons) and after (70 neurons) five injections of MPTP (5 mg/kg every day). It was found that MPTP administration was followed by a clear increase of the discharge frequency of the studied neurons correlated with forelimb movements. The duration of their excitation connected with movement initiation, flexion or extension of limb increased as well.

[Various responses of neurons of the caudate nucleus in alert cats to visual stimulation].

Activity of sixty two neurons of the caudate nucleus to the visual stimuli were recorded in awake cats. It was found that most (52%) of tested neurons gave visual responses of sensory type evoked by the appearance of light stimulus in the visual field and only 11% of them were of the motor type related to the guided eye movement to the target. About a quarter of neurons responded to biologically significant objects revealing nonspecific responses.

[Pathways of visual and auditory information transmission in the caudate nucleus of the cat].

Visual and auditory projections to the caudate nucleus were studied in cat by combination of the HPR method and experimental degeneration of retinal axons. It was shown that visual information comes to the caudate nucleus not only through the well-known polysynaptic pathways from the cerebral cortex, but also through both oligosynaptic (via pulvinar, lateroposterior nucleus, suprageniculate nucleus and nucleus limitans of the thalamus) and disynaptic pathways (via medial and lateral terminal nuclei of the accessory optic tract, pulvinar, pretectum, intermediate superior colliculus layer, supraoptic nucleus) some of which were found for the first time. Direct retinal inputs to the suprageniculate nucleus were found.

[Responses of neurons of the caudate nucleus of the cat during activation of attention by visual objects].

Responses of caudate neurons to visual objects attracting attention to a target were studied in cats. The obtained responses were compared with those to local light stimuli exposed in the visual field during fixation of the gaze. Responses to single and repeated applications of the stimuli caused by both kinds of visual stimulation differed in their latencies and patterns.