[Various aspects of current treatment of patients with alcoholic delirium].

The study is based on the results of clinico-catamnestic evaluation of various methods (two kinds of placebo, antabuse, esperal, and a number of psychotropic drugs and their combinations) of treating 526 chronic alcoholics. Under study there were groups of the addicts comparable in the age, form and duration of the disease, and the degree of personality degradation. The data obtained show that it is preferable to individualize the application of the psychotropic means and combinations with regard to the changes in the addicts' psychics, characteristics of their premorbid personality, and the course of the disease in each particular case.

[Single copy and repetitive nucleotide sequences in the genome of Echinodermata. II. Nucleotide sequence divergence of DNA of echinoderms].

The degree of divergence of short and long repetitive DNA sequences and single copy DNA of five Echinodermata species (sea urchins, starfish, sea-cucumber) was studied by the method of molecular hybridization. Different fractions of 3H-DNA of the sea urchin Strongylocentrotus intermedius were hybridized with the DNA of other species. Thermal stability of the hybridized DNA molecules was determined.

[Single copy and repetitive DNA sequences of Echinodermata. I. Arrangement of DNA sequences of different multiplicity].

Arrangement of repetitive and single copy DNA sequences in the DNA of 8 Echinodermata species (sea urchins, starfishes and sea-cucumber) has been studied. Comparison of the reassociation kinetics of short and long DNA fragments assayed by hydroxyapatite binding indicates that the pattern of DNA sequence organization of all these species is similar to the so called Xenopus pattern found in genomes of most animals and plants. Interspecies differences consist mainly in the quantities of sequences of various repetition degrees and their interspersion with each other and with single copy sequences.

[Differentiated treatment of patients with chronic alcoholism using modern psychotropic drugs].

By using a clinico-catamnestical method the authors studied the effectiveness of different forms of treatment in 159 chronic alcoholic patients (placebo, antabuse and psychotropic drugs). A clinical homogenous group of patients by age, form and duration of the disease, as well as by the degree of degradation, were compared. These data testify to the expediency of a differentiated use of psychotropic drugs depending upon the personality, mental state of the chronic alcoholic patients, the stage and character of the disease in each specific case.