Publications by authors named "V L Vida"

Adult patients with congenital heart disease (ACHD) requiring heart transplantation (HT) usually show complex anatomies, posing surgical challenges. Consequently, we analyzed technical aspects and early and long-term outcomes of additional surgical repairs during HT in ACHD. Forty patients were identified (23 males, median age: 38 years, interquartile range [IQR]: 26-50).

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Article Synopsis
  • - Metabolomics can help identify high-risk infants undergoing surgery for complex congenital heart disease (CHD), as it provides insights into their metabolic profiles and how genetics and environment influence health outcomes.
  • - A systematic review of seven studies, involving 509 infants, showed links between specific metabolites (like amino acids) and adverse outcomes such as mortality and acute kidney injury post-surgery.
  • - While the evidence is limited because of varying study designs and small sample sizes, the research suggests metabolomics could be useful for predicting complications in infants undergoing cardiac surgery.
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Objectives: The functional roles of ventricular dominance and additional ventricular chamber after Fontan operation are still uncertain. We aim to assess and correlate such anatomical features to late clinical outcomes.

Methods: Fontan patients undergoing cardiac MRI and cardiopulmonary exercise test between January 2020 and December 2022 were retrospectively reviewed.

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Article Synopsis
  • The study focuses on the long-term effects of chronic pulmonary insufficiency after surgical repairs for tetralogy of Fallot (TOF) and evaluates new techniques for preserving the pulmonary valve (PV).
  • It includes 134 patients who underwent surgery from 2008 to 2022, comparing those treated with traditional methods and those using PV preservation techniques.
  • Results showed that 73.9% of patients successfully maintained their pulmonary valve function with preservation techniques, leading to improved right ventricular performance and reduced pulmonary insufficiency compared to the traditional method.
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Despite the clinical results of the Fontan operation have certainly improved, it still presents with an inherent surgical risk of death and early morbidities. This is a retrospective clinical study of children undergoing Fontan operation in 9 congenital cardiac centers in Italy between 1990 and 2023. Clinical and surgical data were collected via a dedicated RedCap database.

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