Mechanism of vorticity amplification by elastic waves in a viscoelastic channel flow.

Inertia-less viscoelastic channel flow displays a supercritical nonnormal mode elastic instability due to finite-size perturbations despite its linear stability. The nonnormal mode instability is determined mainly by a direct transition from laminar to chaotic flow, in contrast to normal mode bifurcation leading to a single fastest-growing mode. At higher velocities, transitions to elastic turbulence and further drag reduction flow regimes occur accompanied by elastic waves in three flow regimes.

Universal properties of non-Hermitian viscoelastic channel flows.

An addition of long-chain, flexible polymers strongly affects laminar and turbulent Newtonian flows. In laminar inertia-less viscoelastic channel flow, the supercritical elastic instability of non-normal eigenmodes of non-Hermitian equations at finite-size perturbations leads to chaotic flow. Then three chaotic flow regimes: transition, elastic turbulence (ET), and drag reduction (DR), accompanied by elastic waves, are observed and characterized.

Improved alpharetrovirus-based Gag.MS2 particles for efficient and transient delivery of CRISPR-Cas9 into target cells.

DNA-modifying technologies, such as the CRISPR-Cas9 system, are promising tools in the field of gene and cell therapies. However, high and prolonged expression of DNA-modifying enzymes may cause cytotoxic and genotoxic side effects and is therefore unwanted in therapeutic approaches. Consequently, development of new and potent short-term delivery methods is of utmost importance.

Elastically driven Kelvin-Helmholtz-like instability in straight channel flow.

Originally, Kelvin-Helmholtz instability (KHI) describes the growth of perturbations at the interface separating counterpropagating streams of Newtonian fluids of different densities with heavier fluid at the bottom. Generalized KHI is also used to describe instability of free shear layers with continuous variations of velocity and density. KHI is one of the most studied shear flow instabilities.

Entropic characterization of the coil-stretch transition of polymers in random flows.

Polymer molecules in a flow undergo a coil-stretch phase transition on an increase of the velocity gradients. Model-independent identification and characterization of the transition in a random flow has been lacking so far. Here we suggest to use the entropy of the extension statistics as a proper measure due to strong fluctuations around the transition.