Clinical Accuracy of Serum Neurofilament Light to Differentiate Frontotemporal Dementia from Primary Psychiatric Disorders is Age-Dependent.

Background: Symptoms of behavioral variant frontotemporal dementia (bvFTD) overlap with primary psychiatric disorders (PPD) making diagnosis challenging. Serum neurofilament light (sNfL) is a candidate biomarker to distinguish bvFTD from PPD, but large-scale studies in PPD are lacking.

Objective: Determine factors that influence sNfL from a large database of PPD patients, and test its diagnostic accuracy.

Sex hormone regulation of collagen concentrations in cranial cruciate ligaments of sexually immature male rabbits.

Objective: To investigate the effects of gonadectomy on collagen homeostasis in cranial cruciate ligaments of male rabbits.

Animals: 30 sexually immature (16-week-old) male New Zealand White rabbits.

Procedures: Rabbits were randomly assigned to 5 groups of 6 rabbits each: sexually intact, placebo (control group); castrated, placebo; castrated, testosterone; castrated, dihydrotestosterone; and castrated, 17β-estradiol (E(2)).

Temporal-spatial gait analysis by use of a portable walkway system in healthy Labrador Retrievers at a walk.

Objective: To establish a protocol to collect temporal-spatial gait analysis variables by use of a portable walkway system in Labrador Retrievers at a walk and to determine reference values.

Animals: 56 healthy Labrador Retrievers.

Procedures: 6 passes across the walkway (3 passes in each direction) were recorded.

Prospective comparison of dual-phase technetium-99m-sestamibi scintigraphy and high resolution ultrasonography in the evaluation of abnormal parathyroid glands.

Technetium-99m-sestamibi (MIBI) is a new radionuclide for imaging parathyroid tissue. The purpose of this study was to evaluate parathyroid localization using single radiotracer, dual-phase MIBI scintigraphy and to compare the results to ultrasonography. Twenty-one patients with hyperparathyroidism underwent dual-phase scintigraphy using 25 mCi MIBI and high resolution ultrasonography before parathyroidectomy.

Predictive factors for early mortality after percutaneous endoscopic gastrostomy.

Background: Percutaneous endoscopic gastrostomy (PEG) is a safe access procedure for enteral nutrition. The purpose of this investigation is to identify predictive factors for early mortality after PEG.

Methods: A retrospective review of the hospital records of 416 patients undergoing PEG from June 1, 1989, through December 31, 1991, was conducted.