Publications by authors named "V L H Roberts"
Many human diseases are the result of early developmental defects. As most paediatric diseases and disorders are rare, children are critically underrepresented in research. Functional genomics studies primarily rely on adult tissues and lack critical cell states in specific developmental windows.
View Article and Find Full Text PDFProblem/condition: Splash pads are recreational interactive water venues that spray or jet water on users. Splash pads are intended for children aged <5 years and designed so that water typically does not collect in areas accessible to users, thereby minimizing the risk for drowning. Splash pads were first found to be associated with waterborne disease outbreaks in 1997.
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- Adequate nutrition during pregnancy is essential for fetal brain development, and low protein intake can lead to neurological issues in offspring, which is a major global health concern.
- A study using rhesus macaques showed that reduced maternal protein levels led to structural brain abnormalities and decreased gray matter volume, particularly in areas important for motor control.
- Although significant brain changes were observed through MRI, early behavioral tests at 1 month showed only minor effects, suggesting that the impacts of protein reduction may not immediately translate to behavior.
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- * In a study with 55 pregnant smokers, vitamin C improved umbilical blood flow compared to a placebo, bringing levels closer to those of nonsmokers.
- * RNA-sequencing results indicated that vitamin C altered gene expression related to vascular and cardiac development, hinting at its potential benefits for baby health in situations of prenatal nicotine exposure.
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- Two kittens with type I phimosis underwent a review of their medical records, highlighting clinical signs, surgical techniques, and follow-ups.
- The surgical procedure involved a modified circumferential preputioplasty using 4 and 6 mm Keyes biopsy punches to effectively widen the narrowed preputial orifice.
- Short-term follow-up indicated a minor transient issue, but long-term assessments showed no complications or recurring symptoms, suggesting the technique's reliability and effectiveness for such cases.