Publications by authors named "V L Grandage"
Background: Female childhood cancer survivors with history of bone marrow transplant with or without total body irradiation have increased pregnancy risks. Preconception counselling and early referral to appropriate clinical pathways may improve pregnancy outcomes.
Methods: UK-wide survey of clinicians, promoted via social media and conferences, jointly funded by Action Medical Research/Borne.
Article Synopsis
- * A study of 41 children showed a 43.6% complete remission rate, with most achieving minimal residual disease (MRD) negativity.
- * Venetoclax was effective for bridging patients to transplant, with a 75% success rate, and those starting treatment with MRD <1% had significantly better outcomes in terms of MRD negativity and overall survival.
Objective: To assess the utilisation of and funding structure for fertility preservation for children diagnosed with cancer in the UK.
Design: Survey of paediatric oncologists/haematologists. Questionnaires were sent electronically with reminder notifications to non-responders.