Publications by authors named "V L Fox"
Article Synopsis
- A 3-year-old male on ECMO for respiratory failure developed a fungal infection from a rare pathogen that couldn't be identified by standard testing methods.
- Despite a negative T2Candida panel, blood cultures became positive after 4 days, and traditional identification methods failed, leading to whole genome sequencing (WGS) for precise identification.
- WGS revealed the fungus belonged to the Ustilago genus, and thanks to timely treatment adjustments, the infection was successfully eradicated, highlighting the significance of advanced molecular techniques in diagnosing rare infections.
Cystic fibrosis (CF) is a life-threatening genetic disease characterised by chronic lung infections sustained by opportunistic pathogens such as During the chronic long-lasting lung infections, adapts to the host environment. Hypermutability, mainly due to defects in the DNA repair system, resulting in an increased spontaneous mutation rate, represents a way to boost the rapid adaptation frequently encountered in CF isolates. We selected 609 isolates from 51 patients with CF chronically colonised by to study, by full-length genome sequencing, the longitudinal evolution of the bacterium.
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- The study looked at young kids with a condition called intestinal failure, especially those with a problem called short bowel syndrome (SBS).
- Researchers wanted to see if certain kids, like those with shorter intestines, were more likely to undergo a special test called pan-enteroscopy.
- They found that this test was successful in some kids, particularly those with shorter bowels, and it helped find many issues without causing any harm.
Stress is proposed to be a crucial factor in the onset and presentation of psychosis. The early stage of psychosis provides a window into how stress interacts with the emergence of psychosis. Yet, how people with early psychosis respond to stress remains unclear.
View Article and Find Full Text PDFInvasive group A streptococci infections are increasing worldwide, mainly due to the emm1 lineage M1UK emergence. Although this variant has recently been described in adult Italian patients, its circulation in children has not yet been established. Characterizing by whole genome sequencing 6 invasive group A streptococci strains isolated between 2022 and 2023, we highlighted M1UK lineage circulation in pediatric patients in Italy.
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