Publications by authors named "V L Choo"

Article Synopsis
  • A systematic review and meta-analysis were conducted to investigate how food sources of fructose-containing sugars affect blood pressure (BP) under different energy control conditions.
  • Out of 147 trials involving over 5,200 participants, it was found that excess energy from fructose-containing sugars decreased BP when sugar was added but had no significant effects during substitution, subtraction, or free intake trials.
  • The results suggest that consuming fruit and 100% fruit juice at low levels may help lower BP, while high doses of mixed sources, especially sugar-sweetened beverages, can increase BP, highlighting the influence of food source and energy balance on BP outcomes.
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Background: Sugar-sweetened beverages (SSBs) providing excess energy increase adiposity. The effect of other food sources of sugars at different energy control levels is unclear.

Objectives: To determine the effect of food sources of fructose-containing sugars by energy control on adiposity.

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Article Synopsis
  • Research explores the link between fructose-containing sugars in sugar-sweetened beverages (SSBs) and inflammatory markers, focusing on food source and energy control.
  • A systematic review analyzed 64 controlled trials, looking at how different fructose sources (like sweetened dairy and fruit juice) affect inflammation over varying energy levels.
  • Findings indicate that total fructose-containing sugars reduced C-reactive protein (CRP) in addition trials, while other trial types showed no significant effects on inflammation, suggesting the food source plays a critical role.
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Article Synopsis
  • Excess fructose from sugar-sweetened beverages (SSBs) is linked to increased markers of non-alcoholic fatty liver disease (NAFLD), but the impact of other fructose sources is unclear.
  • The review encompassed 51 trials involving various food sources of fructose, focusing on their effects on intrahepatocellular lipid (IHCL), alanine aminotransferase (ALT), and aspartate aminotransferase (AST).
  • Findings showed that total fructose increased IHCL in addition trials but had no significant effects in substitution or ad libitum trials, and that SSBs were particularly effective in raising IHCL and ALT levels.
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Background: Although fructose as a source of excess calories increases uric acid, the effect of the food matrix is unclear.

Objectives: To assess the effects of fructose-containing sugars by food source at different levels of energy control on uric acid, we conducted a systematic review and meta-analysis of controlled trials.

Methods: MEDLINE, Embase, and the Cochrane Library were searched (through 11 January 2021) for trials ≥ 7 days.

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