Front Pharmacol
December 2024
studies with have demonstrated the antiparasitic activity of , attributed to its naphthoquinones. This study reports on pro-inflammatory changes in mice infected with and correlates these changes with parasitemia and survival. The ethanol extract of (EEEp) was fractionated under reflux to obtain the dichloromethane fraction (FDMEp) and isolated compounds from , relating these to survival time and parasitemia.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
Naphthoquinones eleutherin and isoeleutherin have demonstrated promising antibacterial activity, probably due to their quinone structure, which can generate reactive oxygen species. The study examines the activities of pathogens, such as and , associated with antimicrobial resistance and explores their potential mechanisms of action. The MIC, IC, and MBC were determined.
View Article and Find Full Text PDFNutrients
October 2024
The journal's Editorial Office and Editorial Board are jointly issuing a resolution and removal of the linked to this article [...
View Article and Find Full Text PDFInt J Mol Sci
May 2024
is a species of tick in the family Ixodidae, with equids and capybaras among its preferred hosts. In this study, the acaricidal activity of the essential oil (EO) from and its main component, Dillapiole, were evaluated against larvae of to establish lethal concentration values and assess the effects of these compounds on tick enzymes. Dillapiole exhibited slightly greater activity (LC = 3.
View Article and Find Full Text PDFIpê is a plant of the Bignoniaceae family. Among the compounds extracted from this tree, lapachol is notable because its structural modification allows the production of β-lapachone, which has anticancer properties. The objective of this work was to test this hypothesis at a cellular level in vitro and assess its potential safety for use.
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